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Epi-isozizaene 5-monooxygenase
・ Epi-isozizaene synthase
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Epi-isozizaene 5-monooxygenase : ウィキペディア英語版
Epi-isozizaene 5-monooxygenase

Epi-isozizaene 5-monooxygenase (, ''CYP170A1'') is an enzyme with system name ''(+)-epi-isozizaene,NADPH:oxygen oxidoreductase (5-hydroxylating)''. This enzyme catalyses the following chemical reaction
: (+)-epi-isozizaene + 2 NADPH + 2 H+ + 2 O2 \rightleftharpoons albaflavenone + 2 NADP+ + 3 H2O (overall reaction)
:(1a) (+)-epi-isozizaene + NADPH + H+ + O2 \rightleftharpoons (5S)-albaflavenol + NADP+ + H2O
:(1b) (5S)-albaflavenol + NADPH + H+ + O2 \rightleftharpoons albaflavenone + NADP+ + 2 H2O
:(2a) (+)-epi-isozizaene + NADPH + H+ + O2 \rightleftharpoons (5R)-albaflavenol + NADP+ + H2O
:(2b) (5R)-albaflavenol + NADPH + H+ + O2 \rightleftharpoons albaflavenone + NADP+ + 2 H2O
This cytochrome P450 enzyme is purifid from bacterium ''Streptomyces coelicolor''.
== References ==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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